Mark T. Hamann, PhD, Principal Investigator

Dr. Mark T. Hamann serves as the Charles and Carol Cooper/SmartState Endowed Chair of Drug Discovery, Biomedical Sciences and Public Health at the MUSC Colleges of Pharmacy and Medicine and also holds Adjunct appointments with The University of Maryland’s Institute of Marine and Environmental Technology.

Dr. Hamann began his career in cGMP pharmaceutical manufacturing at Solvay Pharmaceuticals in Baudette, Minnesota, and then completed a Ph.D. degree in Organic Chemistry at the University of Hawaii, under the guidance of the late Professor Paul J. Scheuer. During his graduate studies, he discovered the lead anticancer agent, kahalalide F which entered clinical trials with the leadership of the biotech company PharmaMar.

Dr. Hamann completed Postdoctoral Studies with Prof Bill Baker at McMurdo Station in Antarctica and then spent 20 years as a faculty member and natural products researcher at The University of Mississippi School of Pharmacy. During his research career, Dr. Hamann has published over 250 scientific papers, reviews, book chapters and guided over 100 graduate students/postdoctoral fellows and visiting scholars. Dr. Hamann served as an Associate Editor for Biochimica et Biophysica Acta, General Subjects where he reviewed and edited publications focused on natural product-based therapeutics and new methodologies. His group is actively involved in the isolation, structure determination and optimization through synthesis of natural products and therapeutics with a focus on plant and invertebrate microbiomes. His group is currently working on the preclinical development of a small pipeline of natural products with activity against cancer, emerging infectious diseases, and neuropsychiatric disorders.

He is committed to the success of Sycamore BioPharma and the strategic replacement of petroleum-based fine chemicals with renewables generated through local and regional agriculture and the type of manufacturing available at the facilities at Sycamore BioPharma. This approach to economic development supports both the local economy as well as the reduction of the countries carbon footprint. 


 Tyler Stone, President

Tyler is the principal founder and president of Sycamore BioPharma. He brings a diverse entrepreneurial background to the botanical extraction field as former owner and managing partner of Farmland Conversion Consultants. His time with Farmland provided over 10 years of experience working with various farming operations in the SE in diversifying and expanding their farming operations. His connections within the ag industry and close working relationship with the SC Dept. of Agriculture will enable SBP to recruit and assist farmers and growers in identifying high value botanical products.